Graph-Based Approaches to Protein Structure Comparison

By Marco Mernberger

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The comparison of protein structures is a central task in structural bioinformatics. Drawing upon structural information enables the inference of function for unknown proteins, even without apparent homology on the sequence level. Regarding enzyme function, the conformation of the catalytic site or the binding pocket accomodating bound substrates or ligands is especially i The comparison of protein structures is a central...

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August 12th 2012 by Sudwestdeutscher Verlag Fur Hochschulschriften AG

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