Neurofibromatosis Type 1 Tumourigenesis

By Isis M Atallah

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Neurofibromatosis type 1 (NF1) is one of the most frequent dominantly inherited diseases. NF1 patients harbour an increased risk of developing benign nerve sheath tumours and a 10% lifetime risk of developing malignant peripheral nerve sheath tumours. Molecular mechanisms involved in NF1 malignant transformation are still largely unknown. This book provides an insight into Neurofibromatosis type 1 (NF1) is one of the most...

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July 27th 2012 by Sudwestdeutscher Verlag Fur Hochschulschriften AG

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